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Vasopressin-Independent Regulation of Aquaporin-2 by Tamoxifen in Kidney Collecting Ducts

Arginine vasopressin (AVP) mediates water reabsorption in the kidney collecting ducts through regulation of aquaporin-2 (AQP2). Also, estrogen has been known to regulate AQP2. Consistently, we previously demonstrated that tamoxifen (TAM), a selective estrogen receptor modulator, attenuates the downr...

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Detalles Bibliográficos
Autores principales: Tingskov, Stine Julie, Choi, Hyo-Jung, Holst, Mikkel R., Hu, Shan, Li, Chunling, Wang, Weidong, Frøkiær, Jørgen, Nejsum, Lene N., Kwon, Tae-Hwan, Nørregaard, Rikke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695565/
https://www.ncbi.nlm.nih.gov/pubmed/31447686
http://dx.doi.org/10.3389/fphys.2019.00948