Mechanisms Underlying the Functional Cooperation Between PPARα and GRα to Attenuate Inflammatory Responses

Glucocorticoids (GCs) act via the glucocorticoid receptor (NR3C1, GRα) to combat overshooting responses to infectious stimuli, including lipopolysaccharide (LPS). As such, GCs inhibit the activity of downstream effector cytokines, such as tumor necrosis factor (TNF). PPARα (NR1C1) is a nuclear recep...

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Detalles Bibliográficos
Autores principales: Bougarne, Nadia, Mylka, Viacheslav, Ratman, Dariusz, Beck, Ilse M., Thommis, Jonathan, De Cauwer, Lode, Tavernier, Jan, Staels, Bart, Libert, Claude, De Bosscher, Karolien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695567/
https://www.ncbi.nlm.nih.gov/pubmed/31447832
http://dx.doi.org/10.3389/fimmu.2019.01769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695567/
https://www.ncbi.nlm.nih.gov/pubmed/31447832
http://dx.doi.org/10.3389/fimmu.2019.01769

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