Cargando…

Discovery of (5-Phenylfuran-2-yl)methanamine Derivatives as New Human Sirtuin 2 Inhibitors

Human sirtuin 2 (SIRT2), a member of the sirtuin family, has been considered as a promising drug target in cancer, neurodegenerative diseases, type II diabetes, and bacterial infections. Thus, SIRT2 inhibitors have been involved in effective treatment strategies for related diseases. Using previousl...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Lijiao, Li, Chao, Chen, Wei, Song, Chen, Zhang, Xing, Yang, Fan, Wang, Chen, Zhang, Yuanyuan, Qian, Shan, Wang, Zhouyu, Yang, Lingling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695594/
https://www.ncbi.nlm.nih.gov/pubmed/31357491
http://dx.doi.org/10.3390/molecules24152724