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Discovery of (5-Phenylfuran-2-yl)methanamine Derivatives as New Human Sirtuin 2 Inhibitors
Human sirtuin 2 (SIRT2), a member of the sirtuin family, has been considered as a promising drug target in cancer, neurodegenerative diseases, type II diabetes, and bacterial infections. Thus, SIRT2 inhibitors have been involved in effective treatment strategies for related diseases. Using previousl...
Autores principales: | Wang, Lijiao, Li, Chao, Chen, Wei, Song, Chen, Zhang, Xing, Yang, Fan, Wang, Chen, Zhang, Yuanyuan, Qian, Shan, Wang, Zhouyu, Yang, Lingling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695594/ https://www.ncbi.nlm.nih.gov/pubmed/31357491 http://dx.doi.org/10.3390/molecules24152724 |
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