The Development of Tetrazole Derivatives as Protein Arginine Methyltransferase I (PRMT I) Inhibitors

Protein arginine methyltransferase 1 (PRMT1) can catalyze protein arginine methylation by transferring the methyl group from S-adenosyl-L-methionine (SAM) to the guanidyl nitrogen atom of protein arginine, which influences a variety of biological processes. The dysregulation of PRMT1 is involved in...

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Detalles Bibliográficos
Autores principales: Sun, Yutong, Wang, Zhe, Yang, Hao, Zhu, Xuanli, Wu, Han, Ma, Lu, Xu, Fang, Hong, Wei, Wang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695598/
https://www.ncbi.nlm.nih.gov/pubmed/31390828
http://dx.doi.org/10.3390/ijms20153840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695598/
https://www.ncbi.nlm.nih.gov/pubmed/31390828
http://dx.doi.org/10.3390/ijms20153840

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