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Combination with l-Menthol Enhances Transdermal Penetration of Indomethacin Solid Nanoparticles

This study designed the transdermal formulations containing indomethacin (IMC)—1% IMC was crushed with 0.5% methylcellulose and 5% 2-hydroxypropyl-β-cyclodextrin by the bead mill method, and the milled IMC was gelled with or without 2% l-menthol (a permeation enhancer) by Carbopol(®) 934 (without me...

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Detalles Bibliográficos
Autores principales: Nagai, Noriaki, Ogata, Fumihiko, Yamaguchi, Mizuki, Fukuoka, Yuya, Otake, Hiroko, Nakazawa, Yosuke, Kawasaki, Naohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695644/
https://www.ncbi.nlm.nih.gov/pubmed/31349657
http://dx.doi.org/10.3390/ijms20153644