Interrogating the Essential Bacterial Cell Division Protein FtsQ with Fragments Using Target Immobilized NMR Screening (TINS)

The divisome is a large protein complex that regulates bacterial cell division and therefore represents an attractive target for novel antibacterial drugs. In this study, we report on the ligandability of FtsQ, which is considered a key component of the divisome. For this, the soluble periplasmic do...

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Detalles Bibliográficos
Autores principales: Glas, Marjolein, AB, Eiso, Hollander, Johan, Siegal, Gregg, Luirink, Joen, de Esch, Iwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695665/
https://www.ncbi.nlm.nih.gov/pubmed/31357624
http://dx.doi.org/10.3390/ijms20153684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695665/
https://www.ncbi.nlm.nih.gov/pubmed/31357624
http://dx.doi.org/10.3390/ijms20153684

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