Enhanced Nanoencapsulation of Sepiapterin within PEG-PCL Nanoparticles by Complexation with Triacetyl-Beta Cyclodextrin

In this work, we aimed to improve the encapsulation efficiency of sepiapterin (SP), the natural precursor of the essential cofactor tetrahydrobiopterin (BH4) that displays mild water-solubility and a short biological half-life, within methoxy-poly(ethylene-glycol)-poly(epsilon-caprolactone)(mPEG-PCL...

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Detalles Bibliográficos
Autores principales: Kuplennik, Nataliya, Sosnik, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695667/
https://www.ncbi.nlm.nih.gov/pubmed/31357400
http://dx.doi.org/10.3390/molecules24152715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695667/
https://www.ncbi.nlm.nih.gov/pubmed/31357400
http://dx.doi.org/10.3390/molecules24152715

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