Hydrophobic Interactions Drive Binding between Vascular Endothelial Growth Factor-A (VEGFA) and Polyphenolic Inhibitors

Some polyphenols have been shown to inhibit, at physiological levels, the VEGF-induced VEGF receptor-2 signaling that causes angiogenesis, allegedly by direct interaction with VEGF and reducing the binding to its receptor VEGFR2. Surface plasmon resonance was used to measure the parameters of bindin...

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Detalles Bibliográficos
Autores principales: Perez-Moral, Natalia, Needs, Paul W., Moyle, Christina W.A., Kroon, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695681/
https://www.ncbi.nlm.nih.gov/pubmed/31370204
http://dx.doi.org/10.3390/molecules24152785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695681/
https://www.ncbi.nlm.nih.gov/pubmed/31370204
http://dx.doi.org/10.3390/molecules24152785

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