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Hydrophobic Interactions Drive Binding between Vascular Endothelial Growth Factor-A (VEGFA) and Polyphenolic Inhibitors

Some polyphenols have been shown to inhibit, at physiological levels, the VEGF-induced VEGF receptor-2 signaling that causes angiogenesis, allegedly by direct interaction with VEGF and reducing the binding to its receptor VEGFR2. Surface plasmon resonance was used to measure the parameters of bindin...

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Detalles Bibliográficos
Autores principales:	Perez-Moral, Natalia, Needs, Paul W., Moyle, Christina W.A., Kroon, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695681/ https://www.ncbi.nlm.nih.gov/pubmed/31370204 http://dx.doi.org/10.3390/molecules24152785

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