Mitochondria-Targeting Antioxidant Provides Cardioprotection through Regulation of Cytosolic and Mitochondrial Zn(2+) Levels with Re-Distribution of Zn(2+)-Transporters in Aged Rat Cardiomyocytes

Aging is an important risk factor for cardiac dysfunction. Heart during aging exhibits a depressed mechanical activity, at least, through mitochondria-originated increases in ROS. Previously, we also have shown a close relationship between increased ROS and cellular intracellular free Zn(2+) ([Zn(2+...

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Detalles Bibliográficos
Autores principales: Olgar, Yusuf, Tuncay, Erkan, Turan, Belma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695787/
https://www.ncbi.nlm.nih.gov/pubmed/31382470
http://dx.doi.org/10.3390/ijms20153783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695787/
https://www.ncbi.nlm.nih.gov/pubmed/31382470
http://dx.doi.org/10.3390/ijms20153783

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