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Formation Mechanism of Ion Channel in Channelrhodopsin-2: Molecular Dynamics Simulation and Steering Molecular Dynamics Simulations

Channelrhodopsin-2 (ChR2) is a light-activated and non-selective cationic channel protein that can be easily expressed in specific neurons to control neuronal activity by light. Although ChR2 has been extensively used as an optogenetic tool in neuroscience research, the molecular mechanism of cation...

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Detalles Bibliográficos
Autores principales: Yang, Ting, Zhang, Wenying, Cheng, Jie, Nie, Yanhong, Xin, Qi, Yuan, Shuai, Dou, Yusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695816/
https://www.ncbi.nlm.nih.gov/pubmed/31382458
http://dx.doi.org/10.3390/ijms20153780