Why Does the Type of Halogen Atom Matter for the Radiosensitizing Properties of 5-Halogen Substituted 4-Thio-2′-Deoxyuridines?

Radiosensitizing properties of substituted uridines are of great importance for radiotherapy. Very recently, we confirmed 5-iodo-4-thio-2′-deoxyuridine (ISdU) as an efficient agent, increasing the extent of tumor cell killing with ionizing radiation. To our surprise, a similar derivative of 4-thio-2...

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Detalles Bibliográficos
Autores principales: Spisz, Paulina, Zdrowowicz, Magdalena, Makurat, Samanta, Kozak, Witold, Skotnicki, Konrad, Bobrowski, Krzysztof, Rak, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695862/
https://www.ncbi.nlm.nih.gov/pubmed/31382376
http://dx.doi.org/10.3390/molecules24152819

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695862/
https://www.ncbi.nlm.nih.gov/pubmed/31382376
http://dx.doi.org/10.3390/molecules24152819

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