A Derivate of Benzimidazole-Isoquinolinone Induces SKP2 Transcriptional Inhibition to Exert Anti-Tumor Activity in Glioblastoma Cells

We have previously shown that compound-7g inhibits colorectal cancer cell proliferation and survival by inducing cell cycle arrest and PI3K/AKT/mTOR pathway blockage. However, whether it has the ability to exert antitumor activity in other cancer cells and what is the exact molecular mechanism for i...

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Detalles Bibliográficos
Autores principales: Chen, He-ying, He, Liu-jun, Li, Shi-qiang, Zhang, Ya-jun, Huang, Jiu-hong, Qin, Hong-xia, Wang, Juan-li, Li, Qian-yin, Yang, Dong-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695871/
https://www.ncbi.nlm.nih.gov/pubmed/31357480
http://dx.doi.org/10.3390/molecules24152722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695871/
https://www.ncbi.nlm.nih.gov/pubmed/31357480
http://dx.doi.org/10.3390/molecules24152722

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