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Synthesis and In Vitro Screening of Novel Heterocyclic β-d-Gluco- and β-d-Galactoconjugates as Butyrylcholinesterase Inhibitors

The development of selective butyrylcholinesterase (BChE) inhibitors may improve the treatment of Alzheimer’s disease by increasing lower synaptic levels of the neurotransmitter acetylcholine, which is hydrolysed by acetylcholinesterase, as well as by overexpressed BChE. An increase in the synaptic...

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Detalles Bibliográficos
Autores principales: Baumann, Krešimir, Kordić, Lorena, Močibob, Marko, Šinko, Goran, Tomić, Srđanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695897/
https://www.ncbi.nlm.nih.gov/pubmed/31382668
http://dx.doi.org/10.3390/molecules24152833