Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrates

Cardiomyocytes from human induced pluripotent stem cells (hiPSC-CMs) are the most promising human source with preserved genetic background of healthy individuals or patients. This study aimed to establish a systematic procedure for exploring development of hiPSC-CM functional output to predict genet...

Descripción completa

Detalles Bibliográficos
Autores principales: Pioner, Josè Manuel, Santini, Lorenzo, Palandri, Chiara, Martella, Daniele, Lupi, Flavia, Langione, Marianna, Querceto, Silvia, Grandinetti, Bruno, Balducci, Valentina, Benzoni, Patrizia, Landi, Sara, Barbuti, Andrea, Ferrarese Lupi, Federico, Boarino, Luca, Sartiani, Laura, Tesi, Chiara, Mack, David L., Regnier, Michael, Cerbai, Elisabetta, Parmeggiani, Camilla, Poggesi, Corrado, Ferrantini, Cecilia, Coppini, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695920/
https://www.ncbi.nlm.nih.gov/pubmed/31382622
http://dx.doi.org/10.3390/ijms20153799