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Additive Pharmacological Interaction between Cisplatin (CDDP) and Histone Deacetylase Inhibitors (HDIs) in MDA-MB-231 Triple Negative Breast Cancer (TNBC) Cells with Altered Notch1 Activity—An Isobolographic Analysis

The aim of this study was to investigate the influence of the Notch1 activity level on the pharmacological interaction between cisplatin (CDDP) and two histone deacetylase inhibitors (HDIs)—valproic acid (VPA) and vorinostat (SAHA) in the triple negative breast cancer (TNBC) cells. Stable breast can...

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Detalles Bibliográficos
Autores principales: Wawruszak, Anna, Luszczki, Jarogniew J., Kalafut, Joanna, Okla, Karolina, Halasa, Marta, Rivero-Muller, Adolfo, Stepulak, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696008/
https://www.ncbi.nlm.nih.gov/pubmed/31357442
http://dx.doi.org/10.3390/ijms20153663