Combined Ensemble Docking and Machine Learning in Identification of Therapeutic Agents with Potential Inhibitory Effect on Human CES1

The human carboxylesterase 1 (CES1), responsible for the biotransformation of many diverse therapeutic agents, may contribute to the occurrence of adverse drug reactions and therapeutic failure through drug interactions. The present study is designed to address the issue of potential drug interactio...

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Detalles Bibliográficos
Autores principales: Briand, Eliane, Thomsen, Ragnar, Linnet, Kristian, Rasmussen, Henrik Berg, Brunak, Søren, Taboureau, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696021/
https://www.ncbi.nlm.nih.gov/pubmed/31362390
http://dx.doi.org/10.3390/molecules24152747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696021/
https://www.ncbi.nlm.nih.gov/pubmed/31362390
http://dx.doi.org/10.3390/molecules24152747

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