The Protective Effect of Insulin on Rat Cortical Neurons in Oxidative Stress and Its Dependence on the Modulation of Akt, GSK-3beta, ERK1/2, and AMPK Activities

Insulin is a promising drug for the treatment of diseases associated with brain damage. However, the mechanism of its neuroprotective action is far from being understood. Our aim was to study the insulin-induced protection of cortical neurons in oxidative stress and its mechanism. Immunoblotting, fl...

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Detalles Bibliográficos
Autores principales: Zakharova, Irina O., Sokolova, Tatiana V., Bayunova, Liubov V., Zorina, Inna I., Rychkova, Maria P., Shpakov, Alexander O., Avrova, Natalia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696072/
https://www.ncbi.nlm.nih.gov/pubmed/31362343
http://dx.doi.org/10.3390/ijms20153702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696072/
https://www.ncbi.nlm.nih.gov/pubmed/31362343
http://dx.doi.org/10.3390/ijms20153702

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