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The Role of Sodium Hydrogen Exchanger 1 in Dysregulation of Proton Dynamics and Reprogramming of Cancer Metabolism as a Sequela

Cancer cells have an unusual regulation of hydrogen ion dynamics that are driven by poor vascularity perfusion, regional hypoxia, and increased glycolysis. All these forces synergize/orchestrate together to create extracellular acidity and intracellular alkalinity. Precisely, they lead to extracellu...

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Detalles Bibliográficos
Autores principales: Cardone, Rosa Angela, Alfarouk, Khalid Omer, Elliott, Robert L., Alqahtani, Saad Saeed, Ahmed, Samrein B. M., Aljarbou, Ahmed N., Greco, Maria Raffaella, Cannone, Stefania, Reshkin, Stephan Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696090/
https://www.ncbi.nlm.nih.gov/pubmed/31357694
http://dx.doi.org/10.3390/ijms20153694