Enantioselective Benzylation and Allylation of α-Trifluoromethoxy Indanones under Phase-Transfer Catalysis

The organo-catalyzed enantioselective benzylation reaction of α-trifluoromethoxy indanones afforded α-benzyl-α-trifluoromethoxy indanones with a tetrasubstituted stereogenic carbon center in excellent yield with moderate enantioselectivity (up to 57% ee). Cinchona alkaloid-based chiral phase transfe...

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Detalles Bibliográficos
Autores principales: Liang, Yumeng, Maeno, Mayaka, Zhao, Zhengyu, Shibata, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696116/
https://www.ncbi.nlm.nih.gov/pubmed/31366139
http://dx.doi.org/10.3390/molecules24152774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696116/
https://www.ncbi.nlm.nih.gov/pubmed/31366139
http://dx.doi.org/10.3390/molecules24152774

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