Downregulation of STAT3, β-Catenin, and Notch-1 by Single and Combinations of siRNA Treatment Enhance Chemosensitivity of Wild Type and Doxorubicin Resistant MCF7 Breast Cancer Cells to Doxorubicin

Combinatorial therapeutic strategies using siRNA and small molecules to eradicate tumors are emerging. Targeting multiple signaling pathways decreases the chances of cancer cells switching and adapting new signaling processes that may occur when using a single therapeutic modality. Aberrant function...

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Detalles Bibliográficos
Autores principales: Alshaer, Walhan, Alqudah, Dana A., Wehaibi, Suha, Abuarqoub, Duaa, Zihlif, Malek, Hatmal, Ma’mon M., Awidi, Abdalla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696135/
https://www.ncbi.nlm.nih.gov/pubmed/31357721
http://dx.doi.org/10.3390/ijms20153696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696135/
https://www.ncbi.nlm.nih.gov/pubmed/31357721
http://dx.doi.org/10.3390/ijms20153696

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