A Structure—Activity Relationship Study of Bis-Benzamides as Inhibitors of Androgen Receptor—Coactivator Interaction

The interaction between androgen receptor (AR) and coactivator proteins plays a critical role in AR-mediated prostate cancer (PCa) cell growth, thus its inhibition is emerging as a promising strategy for PCa treatment. To develop potent inhibitors of the AR–coactivator interaction, we have designed...

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Detalles Bibliográficos
Autores principales: Lee, Tae-Kyung, Ravindranathan, Preethi, Sonavane, Rajni, Raj, Ganesh V., Ahn, Jung-Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696232/
https://www.ncbi.nlm.nih.gov/pubmed/31370197
http://dx.doi.org/10.3390/molecules24152783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696232/
https://www.ncbi.nlm.nih.gov/pubmed/31370197
http://dx.doi.org/10.3390/molecules24152783

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