Novel Benzothiazole-Based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer’s Disease Treatment

It has long been established that mitochondrial dysfunction in Alzheimer’s disease (AD) patients can trigger pathological changes in cell metabolism by altering metabolic enzymes such as the mitochondrial 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10), also known as amyloid-binding alcohol deh...

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Detalles Bibliográficos
Autores principales: Aitken, Laura, Benek, Ondrej, McKelvie, Brogan E., Hughes, Rebecca E., Hroch, Lukas, Schmidt, Monika, Major, Louise L., Vinklarova, Lucie, Kuca, Kamil, Smith, Terry K., Musilek, Kamil, Gunn-Moore, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696238/
https://www.ncbi.nlm.nih.gov/pubmed/31362457
http://dx.doi.org/10.3390/molecules24152757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696238/
https://www.ncbi.nlm.nih.gov/pubmed/31362457
http://dx.doi.org/10.3390/molecules24152757

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