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Novel Benzothiazole-Based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer’s Disease Treatment
It has long been established that mitochondrial dysfunction in Alzheimer’s disease (AD) patients can trigger pathological changes in cell metabolism by altering metabolic enzymes such as the mitochondrial 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10), also known as amyloid-binding alcohol deh...
Autores principales: | Aitken, Laura, Benek, Ondrej, McKelvie, Brogan E., Hughes, Rebecca E., Hroch, Lukas, Schmidt, Monika, Major, Louise L., Vinklarova, Lucie, Kuca, Kamil, Smith, Terry K., Musilek, Kamil, Gunn-Moore, Frank J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696238/ https://www.ncbi.nlm.nih.gov/pubmed/31362457 http://dx.doi.org/10.3390/molecules24152757 |
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