SUSD2 Proteolytic Cleavage Requires the GDPH Sequence and Inter-Fragment Disulfide Bonds for Surface Presentation of Galectin-1 on Breast Cancer Cells

Galectin-1 (Gal-1) is a 14 kDa protein that has been well characterized for promoting cancer metastasis and tumor immune evasion. By localizing to the cancer cell surface, Gal-1 induces T cell apoptosis through binding T cell surface receptors. The transmembrane protein, Sushi Domain Containing 2 (S...

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Detalles Bibliográficos
Autores principales: Patrick, Mitch E., Egland, Kristi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696261/
https://www.ncbi.nlm.nih.gov/pubmed/31387209
http://dx.doi.org/10.3390/ijms20153814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696261/
https://www.ncbi.nlm.nih.gov/pubmed/31387209
http://dx.doi.org/10.3390/ijms20153814

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