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MMI-0100 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice through Targeting MK2 Pathway

Backgrounds: This study aimed to investigate the protective effects of MMI-0100, a cell-penetrating peptide inhibitor of MAPK-activated protein kinase II (MK2), on acute colitis induced by dextran sodium sulfate (DSS). Mice were injected intraperitoneally with different doses of MMI-0100 (0.5 and 1...

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Detalles Bibliográficos
Autores principales: Wang, Zhe, Liang, Xue Ya, Chang, Xin, Nie, Yao Yan, Guo, Chen, Jiang, Jin Hong, Chang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696270/
https://www.ncbi.nlm.nih.gov/pubmed/31382637
http://dx.doi.org/10.3390/molecules24152832