A Galactoside-Binding Protein Tricked into Binding Unnatural Pyranose Derivatives: 3-Deoxy-3-Methyl-Gulosides Selectively Inhibit Galectin-1

Galectins are a family of galactoside-recognizing proteins involved in different galectin-subtype-specific inflammatory and tumor-promoting processes, which motivates the development of inhibitors that are more selective galectin inhibitors than natural ligand fragments. Here, we describe the synthe...

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Detalles Bibliográficos
Autores principales: Pal, Kumar Bhaskar, Mahanti, Mukul, Leffler, Hakon, Nilsson, Ulf J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696278/
https://www.ncbi.nlm.nih.gov/pubmed/31382488
http://dx.doi.org/10.3390/ijms20153786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696278/
https://www.ncbi.nlm.nih.gov/pubmed/31382488
http://dx.doi.org/10.3390/ijms20153786

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