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Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer’s Disease

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease which is still poorly understood. The drugs currently used against AD, mainly acetylcholinesterase inhibitors (AChEI), are considered clinically insufficient and are responsible for deleterious side effects. AChE is, however, cur...

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Detalles Bibliográficos
Autores principales: Toublet, François-Xavier, Lecoutey, Cédric, Lalut, Julien, Hatat, Bérénice, Davis, Audrey, Since, Marc, Corvaisier, Sophie, Freret, Thomas, Sopkova de Oliveira Santos, Jana, Claeysen, Sylvie, Boulouard, Michel, Dallemagne, Patrick, Rochais, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696315/
https://www.ncbi.nlm.nih.gov/pubmed/31370232
http://dx.doi.org/10.3390/molecules24152786