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Strategies to Increase On-Target and Reduce Off-Target Effects of the CRISPR/Cas9 System in Plants
The CRISPR/Cas9 system (clustered regularly interspaced short palindromic repeat-associated protein 9) is a powerful genome-editing tool in animals, plants, and humans. This system has some advantages, such as a high on-target mutation rate (targeting efficiency), less cost, simplicity, and high-eff...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696359/ https://www.ncbi.nlm.nih.gov/pubmed/31366028 http://dx.doi.org/10.3390/ijms20153719 |