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Association of Polymorphisms in Genes Involved in One-Carbon Metabolism with MTHFR Methylation Levels

Methylenetetrahydrofolate reductase (MTHFR) is a pivotal enzyme in the one-carbon metabolism, a metabolic pathway required for DNA synthesis and methylation reactions. MTHFR hypermethylation, resulting in reduced gene expression, can contribute to several human disorders, but little is still known a...

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Detalles Bibliográficos
Autores principales: Coppedè, Fabio, Stoccoro, Andrea, Tannorella, Pierpaola, Gallo, Roberta, Nicolì, Vanessa, Migliore, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696388/
https://www.ncbi.nlm.nih.gov/pubmed/31370354
http://dx.doi.org/10.3390/ijms20153754