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Association of Polymorphisms in Genes Involved in One-Carbon Metabolism with MTHFR Methylation Levels
Methylenetetrahydrofolate reductase (MTHFR) is a pivotal enzyme in the one-carbon metabolism, a metabolic pathway required for DNA synthesis and methylation reactions. MTHFR hypermethylation, resulting in reduced gene expression, can contribute to several human disorders, but little is still known a...
Autores principales: | Coppedè, Fabio, Stoccoro, Andrea, Tannorella, Pierpaola, Gallo, Roberta, Nicolì, Vanessa, Migliore, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696388/ https://www.ncbi.nlm.nih.gov/pubmed/31370354 http://dx.doi.org/10.3390/ijms20153754 |
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