Cargando…
Revisiting the Role of LXRs in PUFA Metabolism and Phospholipid Homeostasis
Liver X receptors (LXRs) play a pivotal role in fatty acid (FA) metabolism. So far, the lipogenic consequences of in vivo LXR activation, as characterized by a major hepatic steatosis, has constituted a limitation to the clinical development of pharmacological LXR agonists. However, recent studies p...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696407/ https://www.ncbi.nlm.nih.gov/pubmed/31382500 http://dx.doi.org/10.3390/ijms20153787 |