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Revisiting the Role of LXRs in PUFA Metabolism and Phospholipid Homeostasis

Liver X receptors (LXRs) play a pivotal role in fatty acid (FA) metabolism. So far, the lipogenic consequences of in vivo LXR activation, as characterized by a major hepatic steatosis, has constituted a limitation to the clinical development of pharmacological LXR agonists. However, recent studies p...

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Detalles Bibliográficos
Autores principales: Jalil, Antoine, Bourgeois, Thibaut, Ménégaut, Louise, Lagrost, Laurent, Thomas, Charles, Masson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696407/
https://www.ncbi.nlm.nih.gov/pubmed/31382500
http://dx.doi.org/10.3390/ijms20153787