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Revisiting the Role of LXRs in PUFA Metabolism and Phospholipid Homeostasis
Liver X receptors (LXRs) play a pivotal role in fatty acid (FA) metabolism. So far, the lipogenic consequences of in vivo LXR activation, as characterized by a major hepatic steatosis, has constituted a limitation to the clinical development of pharmacological LXR agonists. However, recent studies p...
Autores principales: | Jalil, Antoine, Bourgeois, Thibaut, Ménégaut, Louise, Lagrost, Laurent, Thomas, Charles, Masson, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696407/ https://www.ncbi.nlm.nih.gov/pubmed/31382500 http://dx.doi.org/10.3390/ijms20153787 |
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