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Roles of p53 Family Structure and Function in Non-Canonical Response Element Binding and Activation

The p53 canonical consensus sequence is a 10-bp repeat of PuPuPuC(A/T)(A/T)GPyPyPy, separated by a spacer with up to 13 bases. C(A/T)(A/T)G is the core sequence and purine (Pu) and pyrimidine (Py) bases comprise the flanking sequence. However, in the p53 noncanonical sequences, there are many variat...

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Detalles Bibliográficos
Autores principales: Cai, Bi-He, Chao, Chung-Faye, Huang, Hsiang-Chi, Lee, Hsueh-Yi, Kannagi, Reiji, Chen, Jang-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696488/
https://www.ncbi.nlm.nih.gov/pubmed/31357595
http://dx.doi.org/10.3390/ijms20153681