Claudin-7 Modulates Cl(−) and Na(+) Homeostasis and WNK4 Expression in Renal Collecting Duct Cells

Claudin-7 knockout (CLDN7(−/−)) mice display renal salt wasting and dehydration phenotypes. To address the role of CLDN7 in kidneys, we established collecting duct (CD) cell lines from CLDN7(+/+) and CLDN7(−/−) mouse kidneys. We found that deletion of CLDN7 increased the transepithelial resistance (...

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Detalles Bibliográficos
Autores principales: Fan, Junming, Tatum, Rodney, Hoggard, John, Chen, Yan-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696617/
https://www.ncbi.nlm.nih.gov/pubmed/31382627
http://dx.doi.org/10.3390/ijms20153798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696617/
https://www.ncbi.nlm.nih.gov/pubmed/31382627
http://dx.doi.org/10.3390/ijms20153798

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