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Claudin-7 Modulates Cl(−) and Na(+) Homeostasis and WNK4 Expression in Renal Collecting Duct Cells
Claudin-7 knockout (CLDN7(−/−)) mice display renal salt wasting and dehydration phenotypes. To address the role of CLDN7 in kidneys, we established collecting duct (CD) cell lines from CLDN7(+/+) and CLDN7(−/−) mouse kidneys. We found that deletion of CLDN7 increased the transepithelial resistance (...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696617/ https://www.ncbi.nlm.nih.gov/pubmed/31382627 http://dx.doi.org/10.3390/ijms20153798 |