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Specific Inhibition of CYP4A Alleviates Myocardial Oxidative Stress and Apoptosis Induced by Advanced Glycation End-Products

High exposure to advanced glycation end-products (AGEs) may induce cardiotoxicity. However, the effects and mechanisms remain to be further clarified. CYP4A plays an important role in the pathophysiological process of myocardial abnormalities by modulating oxidative stress and apoptosis (OS/Apop) si...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Wang, Li, He, Jinlong, Li, Shanshan, Yang, Xiaojing, Sun, Pengyuan, Yuan, Yuhui, Peng, Jinyong, Yan, Jinsong, Du, Jianling, Li, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696796/
https://www.ncbi.nlm.nih.gov/pubmed/31447674
http://dx.doi.org/10.3389/fphar.2019.00876