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Specific Inhibition of CYP4A Alleviates Myocardial Oxidative Stress and Apoptosis Induced by Advanced Glycation End-Products
High exposure to advanced glycation end-products (AGEs) may induce cardiotoxicity. However, the effects and mechanisms remain to be further clarified. CYP4A plays an important role in the pathophysiological process of myocardial abnormalities by modulating oxidative stress and apoptosis (OS/Apop) si...
Autores principales: | Wang, Rui, Wang, Li, He, Jinlong, Li, Shanshan, Yang, Xiaojing, Sun, Pengyuan, Yuan, Yuhui, Peng, Jinyong, Yan, Jinsong, Du, Jianling, Li, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696796/ https://www.ncbi.nlm.nih.gov/pubmed/31447674 http://dx.doi.org/10.3389/fphar.2019.00876 |
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