Combined melatonin and poricoic acid A inhibits renal fibrosis through modulating the interaction of Smad3 and β-catenin pathway in AKI-to-CKD continuum

BACKGROUND: Acute kidney injury (AKI) is one of the major risk factors for progression to chronic kidney disease (CKD) and renal fibrosis. However, effective therapies remain poorly understood. Here, we examined the renoprotective effects of melatonin and poricoic acid A (PAA) isolated from the surf...

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Detalles Bibliográficos
Autores principales: Chen, Dan-Qian, Cao, Gang, Zhao, Hui, Chen, Lin, Yang, Tian, Wang, Ming, Vaziri, Nosratola D., Guo, Yan, Zhao, Ying-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696851/
https://www.ncbi.nlm.nih.gov/pubmed/31452866
http://dx.doi.org/10.1177/2040622319869116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696851/
https://www.ncbi.nlm.nih.gov/pubmed/31452866
http://dx.doi.org/10.1177/2040622319869116

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