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GRP78 regulates CD44v membrane homeostasis and cell spreading in tamoxifen-resistant breast cancer

GRP78 conducts protein folding and quality control in the ER and shows elevated expression and cell surface translocation in advanced tumors. However, the underlying mechanisms enabling GRP78 to exert novel signaling functions at cell surface are just emerging. CD44 is a transmembrane protein and an...

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Detalles Bibliográficos
Autores principales: Tseng, Chun-Chih, Stanciauskas, Ramunas, Zhang, Pu, Woo, Dennis, Wu, Kaijin, Kelly, Kevin, Gill, Parkash S, Yu, Min, Pinaud, Fabien, Lee, Amy S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696983/
https://www.ncbi.nlm.nih.gov/pubmed/31416894
http://dx.doi.org/10.26508/lsa.201900377