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Beyond sequence homology: Cellular biology limits the potential of XIST to act as a miRNA sponge
INTRODUCTION: The sponging of microRNAs by a long non-coding RNA (lncRNA) away from their coding gene targets is a conceptually-simple, yet biologically-complex method of lncRNA-mediated gene regulation. Currently, predictions of genes that participate in sponge-based regulation are largely based on...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697314/ https://www.ncbi.nlm.nih.gov/pubmed/31419261 http://dx.doi.org/10.1371/journal.pone.0221371 |