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Peripheral PD-1+CD56+ T-cell frequencies correlate with outcome in stage IV melanoma under PD-1 blockade

Immune checkpoint blockade with anti-PD-1 antibodies is showing great promise for patients with metastatic melanoma and other malignancies, but despite good responses by some patients who achieve partial or complete regression, many others still do not respond. Here, we sought peripheral blood T-cel...

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Detalles Bibliográficos
Autores principales: Bochem, Jonas, Zelba, Henning, Amaral, Teresa, Spreuer, Janine, Soffel, Daniel, Eigentler, Thomas, Wagner, Nikolaus Benjamin, Uslu, Ugur, Terheyden, Patrick, Meier, Friedegund, Garbe, Claus, Pawelec, Graham, Weide, Benjamin, Wistuba-Hamprecht, Kilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697319/
https://www.ncbi.nlm.nih.gov/pubmed/31419253
http://dx.doi.org/10.1371/journal.pone.0221301