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Enrichment drives emergence of functional columns and improves sensory coding in the whisker map in L2/3 of mouse S1

Sensory maps in layer (L) 2/3 of rodent cortex lack precise functional column boundaries, and instead exhibit locally heterogeneous (salt-and-pepper) tuning superimposed on smooth global topography. Could this organization be a byproduct of impoverished experience in laboratory housing? We compared...

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Detalles Bibliográficos
Autores principales: LeMessurier, Amy M, Laboy-Juárez, Keven J, McClain, Kathryn, Chen, Shilin, Nguyen, Theresa, Feldman, Daniel E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697414/
https://www.ncbi.nlm.nih.gov/pubmed/31418693
http://dx.doi.org/10.7554/eLife.46321