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Nuclear ELAC2 overexpression is associated with increased hazard for relapse after radical prostatectomy

ELAC2 is a ubiquitously expressed enzyme potentially involved in tRNA processing and cell signaling pathways. Mutations of the ELAC2 gene have been found to confer increased prostate cancer susceptibility in families. ELAC2 protein expression was analyzed by immunohistochemistry in 9,262 patients an...

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Detalles Bibliográficos
Autores principales: Schroeder, Cornelia, Navid-Hill, Elham, Meiners, Jan, Hube-Magg, Claudia, Kluth, Martina, Makrypidi-Fraune, Georgia, Simon, Ronald, Büscheck, Franziska, Luebke, Andreas M., Goebel, Cosima, Lang, Dagmar S., Weidemann, Sören, Neubauer, Emily, Hinsch, Andrea, Jacobsen, Frank, Lebok, Patrick, Michl, Uwe, Pehrke, Dirk, Huland, Hartwig, Graefen, Markus, Schlomm, Thorsten, Sauter, Guido, Höflmayer, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697635/
https://www.ncbi.nlm.nih.gov/pubmed/31452838
http://dx.doi.org/10.18632/oncotarget.27132