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Nuclear ELAC2 overexpression is associated with increased hazard for relapse after radical prostatectomy
ELAC2 is a ubiquitously expressed enzyme potentially involved in tRNA processing and cell signaling pathways. Mutations of the ELAC2 gene have been found to confer increased prostate cancer susceptibility in families. ELAC2 protein expression was analyzed by immunohistochemistry in 9,262 patients an...
Autores principales: | Schroeder, Cornelia, Navid-Hill, Elham, Meiners, Jan, Hube-Magg, Claudia, Kluth, Martina, Makrypidi-Fraune, Georgia, Simon, Ronald, Büscheck, Franziska, Luebke, Andreas M., Goebel, Cosima, Lang, Dagmar S., Weidemann, Sören, Neubauer, Emily, Hinsch, Andrea, Jacobsen, Frank, Lebok, Patrick, Michl, Uwe, Pehrke, Dirk, Huland, Hartwig, Graefen, Markus, Schlomm, Thorsten, Sauter, Guido, Höflmayer, Doris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697635/ https://www.ncbi.nlm.nih.gov/pubmed/31452838 http://dx.doi.org/10.18632/oncotarget.27132 |
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