ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations

The ALK gene is a major oncogene of neuroblastoma cases exhibiting ALK activating mutations. Here, we characterized two neuroblastoma cell lines established from a stage 4 patient at diagnosis either from the primary tumor (PT) or from the bone marrow (BM). Both cell lines exhibited similar genomic...

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Detalles Bibliográficos
Autores principales: Durand, Simon, Pierre-Eugène, Cécile, Mirabeau, Olivier, Louis-Brennetot, Caroline, Combaret, Valérie, Colmet-Daage, Léo, Blanchard, Orphée, Bellini, Angela, Daudigeos-Dubus, Estelle, Raynal, Virginie, Schleiermacher, Gudrun, Baulande, Sylvain, Delattre, Olivier, Janoueix-Lerosey, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697636/
https://www.ncbi.nlm.nih.gov/pubmed/31452835
http://dx.doi.org/10.18632/oncotarget.27119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697636/
https://www.ncbi.nlm.nih.gov/pubmed/31452835
http://dx.doi.org/10.18632/oncotarget.27119

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