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Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins

The MYC family oncogenes (MYC, MYCN, and MYCL) contribute to the genesis of many human cancers. Among them, amplification of the MYCN gene and over-expression of N-Myc protein are the most reliable risk factors in neuroblastoma patients. On the other hand, we previously found that a peptide derived...

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Detalles Bibliográficos
Autores principales: Sasada, Manabu, Iyoda, Takuya, Asayama, Tatsufumi, Suenaga, Yusuke, Sakai, Shunsuke, Kase, Naoya, Kodama, Hiroaki, Yokoi, Sana, Isohama, Yoichiro, Fukai, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697639/
https://www.ncbi.nlm.nih.gov/pubmed/31452837
http://dx.doi.org/10.18632/oncotarget.27131