Thapsigargin induces apoptosis in adrenocortical carcinoma by activating endoplasmic reticulum stress and the JNK signaling pathway: an in vitro and in vivo study

OBJECTIVE: Thapsigargin (TG) is a natural product that exists in most parts of the plant Thapsia garganica L. and possesses potential anticancer activities against variety tumor cell lines. TG induces endoplasmic reticulum (ER) stress and apoptosis by inhibiting cancer growth. However, the antineopl...

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Detalles Bibliográficos
Autores principales: Wu, Lili, Huang, Xuemei, Kuang, Yaqi, Xing, Zengmiao, Deng, Xiujun, Luo, Zuojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697672/
https://www.ncbi.nlm.nih.gov/pubmed/31496655
http://dx.doi.org/10.2147/DDDT.S209947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697672/
https://www.ncbi.nlm.nih.gov/pubmed/31496655
http://dx.doi.org/10.2147/DDDT.S209947

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