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Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab

The identification of exclusive markers to target HIV-reservoir cells will represent a significant advance in the search for therapies to cure HIV. Here, we identify the B lymphocyte antigen CD20 as a marker for HIV-infected cells in vitro and in vivo. The CD20 molecule is dimly expressed in a subpo...

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Detalles Bibliográficos
Autores principales: Serra-Peinado, Carla, Grau-Expósito, Judith, Luque-Ballesteros, Laura, Astorga-Gamaza, Antonio, Navarro, Jordi, Gallego-Rodriguez, Jenny, Martin, Mario, Curran, Adrià, Burgos, Joaquin, Ribera, Esteban, Raventós, Berta, Willekens, Rein, Torrella, Ariadna, Planas, Bibiana, Badía, Rosa, Garcia, Felipe, Castellví, Josep, Genescà, Meritxell, Falcó, Vicenç, Buzon, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697690/
https://www.ncbi.nlm.nih.gov/pubmed/31420544
http://dx.doi.org/10.1038/s41467-019-11556-4